Spider-Man / Peter Parker

Andrew Garfield

Acting

Gwen Stacy

Emma Stone

Acting

The Lizard / Dr. Curt Connors

Rhys Ifans

Acting

Captain Stacy

Denis Leary

Acting

Uncle Ben

Martin Sheen

Acting

Aunt May

Sally Field

Acting

Rajit Ratha

Irrfan Khan

Acting

Richard Parker

Campbell Scott

Acting

Mary Parker

Embeth Davidtz

Acting

Flash Thompson

Chris Zylka

Acting

Peter Parker (Age 4)

Max Charles

Acting

Jack's Father

C. Thomas Howell

Acting

Jack

Jake Keiffer

Acting

Helen Stacy

Kari Coleman

Acting

Store Clerk

Michael Barra

Acting

Cash Register Thief

Leif Gantvoort

Acting

Gordon

Andy Pessoa

Acting

Missy Kallenback

Hannah Marks

Acting

Hot Girl

Kelsey Asbille

Acting

Mr. Cramer

Kevin McCorkle

Acting

Physics Nerd

Andy Gladbach

Sound

Physics Nerd

Ring Hendricks-Tellefsen

Acting

Miss Ritter

Barbara Eve Harris

Acting

School Librarian

Stan Lee

Writing

Nicky's Girlfriend

Danielle Burgio

Acting

Nicky

Tom Waite

Acting

Car Thief

Keith Campbell

Crew

Car Thief Cop

Steve DeCastro

Acting

Receptionist

Jill Flint

Acting

OsCorp Intern

Mark Daugherty

Acting

Rodrigo Guevara

Milton González

Acting

Howard Stacy

Skyler Gisondo

Acting

Philip Stacy

Charlie DePew

Acting

Simon Stacy

Jacob Rodier

Acting

Construction Worker

Vincent Laresca

Acting

Taxi Driver

Damien Lemon

Acting

Police Officer with Sketch

Ty Upshaw

Acting

Police Officer

James Chen

Acting

Officer (SWAT)

Alexander Bedria

Acting

Sheila (Subway)

Tia Texada

Acting

Subway Guy

Jay Caputo

Crew

Newscaster (News Chopper)

John Burke

Acting

Principal

Terry Bozeman

Acting

Second Girl (Subway)

Jennifer Lyons

Acting

Man in the Shadows

Michael Massee

Acting

Ariel

Amber Stevens West

Acting

Scientist (uncredited)

Max Bogner

Acting

Lab Technician (uncredited)

Ethan Cohn

Acting

Billy Connors (uncredited)

Miles Elliot

Acting

Cheerleader (uncredited)

Miranda LaDawn Hill

Acting

Goth Girl (uncredited)

Amanda MacDonald

Acting

Tina (uncredited)

Maury Morgan

Acting

Alfie (uncredited)

Michael Papajohn

Acting