George Herman 'Babe' Ruth

William Bendix

Acting

Claire Hodgson Ruth

Claire Trevor

Acting

Brother Matthias

Charles Bickford

Acting

Phil Conrad

Sam Levene

Acting

Jack Dunn

William Frawley

Acting

Nightclub Singer

Gertrude Niesen

Acting

Miller Huggins

Fred Lightner

Acting

Western Union Boy

Stanley Clements

Acting

Babe Ruth as a Boy (as Bobby Ellis)

Robert Ellis

Acting

Gambler Dalton

Lloyd Gough

Acting

Colonel Jacob Ruppert

Matt Briggs

Acting

Dr. Menzies

Paul Cavanagh

Acting

Boston Braves' Rookie

Warren Douglas

Acting

Bill Carrigan, Red Sox Manager

Pat Flaherty

Acting

Mark Koenig

Mark Koenig

Acting

Boston Braves' coach

Richard Lane

Acting

Umpire Ziggy Sears

Ziggy Sears

Acting

Bucky Harris - Baseball Player

Bucky Harris

Acting

Harry Wismer - Sports Announcer

Harry Wismer

Acting

Mel Allen - New York Yankees Radio Announcer

Mel Allen

Acting

H. V. Kaltenborn - Radio News Commentator

H.V. Kaltenborn

Acting

Narrator

Knox Manning

Acting

Barfly (uncredited)

Al Bain

Acting

Reporter (uncredited)

Oliver Crawford

Acting