Eric Brooks / Blade

Wesley Snipes

Acting

Abigail Whistler

Jessica Biel

Acting

Hannibal King

Ryan Reynolds

Acting

Abraham Whistler

Kris Kristofferson

Acting

Dracula / Drake

Dominic Purcell

Acting

Danica Talos

Parker Posey

Acting

Sommerfield

Natasha Lyonne

Acting

Ray Cumberland

James Remar

Acting

Dr. Edgar Vance

John Michael Higgins

Acting

Hedges

Patton Oswalt

Acting

Asher Talos

Callum Keith Rennie

Acting

Jarko Grimwood

Paul Levesque

Acting

Virago

Françoise Yip

Acting

Chief Martin Vreede

Mark Berry

Acting

Wolfe

Paul Anthony

Acting

Wilson Hale

Michael Anthony Rawlins

Acting

Zoe

Ginger Page

Acting

Bentley Tittle

Eric Bogosian

Acting

Goth Vixen Wannabe

Erica Cerra

Acting

Stone

Clay Cullen

Crew

Woman Bystander

Shannon Powell

Acting

Dingo

Birkett Turton

Acting

Drake Creature (uncredited)

Brian Steele

Acting

Caulder

Christopher Heyerdahl

Acting