Spot Helperman / Scott Leadready II / Scott Manly-Manning (voice)

Nathan Lane

Acting

Dr. Ivan Krank (voice)

Kelsey Grammer

Acting

Leonard Amadeus Helperman (voice)

Shaun Fleming

Acting

Mrs. Mary Lou Moira Angela Darling Helperman (voice)

Debra Jo Rupp

Acting

Mr. Jolly (voice)

David Ogden Stiers

Acting

Pretty Boy (voice)

Jerry Stiller

Acting

Dennis (voice)

Paul Reubens

Acting

Adele (voice)

Megan Mullally

Acting

Principal Crosby Strickler (voice)

Wallace Shawn

Acting

Ian Wazselewski (voice)

Rob Paulsen

Acting

Barry Anger (voice)

Jay Thomas

Acting

Mrs. Boogin (voice)

Estelle Harris

Acting

Marsha / Marcia (voice)

Genie Francis

Acting

John / Juan (voice)

Anthony Geary

Acting

The Blue Fairy (voice)

Rosalyn Landor

Acting

Beefeater (voice)

David Maples

Writing

Trevor / Taylor / Tyler (voice)

Pamela Adlon

Acting

Father (voice)

Timothy Stack

Acting

Little Girl (voice)

Emma Steinkellner

Acting

Officer White (voice)

Ken Swofford

Acting

Younghee (voice)

Lauren Tom

Acting

Leslie Dunkling (voice)

Mae Whitman

Acting

Conductor (voice)

Kevin Michael Richardson

Acting