Larry "Doc" Sportello

Joaquin Phoenix

Acting

Lt. Det. Christian F. "Bigfoot" Bjornsen

Josh Brolin

Acting

Coy Harlingen

Owen Wilson

Acting

Shasta Fay Hepworth

Katherine Waterston

Acting

Deputy D.A. Penny Kimball

Reese Witherspoon

Acting

Sauncho Smilax, Esq.

Benicio del Toro

Acting

Hope Harlingen

Jena Malone

Acting

Sortilège, who is also the narrator

Joanna Newsom

Acting

Denis

Jordan Christian Hearn

Acting

Jade

Hong Chau

Acting

Aunt Reet

Jeannie Berlin

Acting

Petunia Leeway

Maya Rudolph

Acting

Tariq Khalil

Michael Kenneth Williams

Acting

Dr. Rudy Blatnoyd, D.D.S.

Martin Short

Acting

Japonica Fenway

Sasha Pieterse

Acting

Crocker Fenway

Martin Donovan

Acting

Michael Z. "Mickey" Wolfmann

Eric Roberts

Acting

Sloane Wolfmann

Serena Scott Thomas

Acting

Glenn Charlock

Christopher Allen Nelson

Costume & Make-Up

Agent Flatweed

Sam Jaeger

Acting

Agent Borderline

Timothy Simons

Acting

Chlorinda

Jillian Bell

Acting

Ensenada Slim

Taylor Bonin

Camera

Dr. Buddy Tubeside

Martin Dew

Acting

Bambi

Shannon Collis

Acting

News Reporter

Catherine Haena Kim

Acting

Amethyst Harlingen

Vivienne Khaledi

Acting

Luz

Yvette Yates Redick

Acting

Riggs Warbling

Andrew Simpson

Acting

Cop with Bigfoot

Joe Dioletto

Acting

Burke Stodger (archive footage)

Jack Kelly

Acting

The Boards

The Growlers

Acting

Clancy Charlock

Belladonna

Acting

Howdy Doper's Phone Voice (voice)

Alina Gatti

Directing

Xandra

Elaine Tan

Acting

LAPD Officer #1

Wilson Bethel

Acting

LAPD Officer #2

Anders Holm

Acting

Bigfoot's Kid

Emmet Unverzagt

Acting

Dr. Lily Hammer

Erica Sullivan

Acting

Dr. Threeply's Assistant #1

Eva Fisher

Acting

Dr. Threeply's Assistant #2

Jackie Michele Johnson

Acting

Kimberly

Katie Schwartz

Acting

Dr. Igor

Charley Morgan

Acting

Puck Beaverton

Keith Jardine

Acting

Mrs. Chastity Bjornsen

Delaina Mitchell

Acting

Rhus Frothingham

Michael Cotter

Acting

Adrian Prussia

Peter McRobbie

Acting

Adrian Prussia's Secretary

Shannon C. Sullivan

Acting

Golden Fang Mother

Samantha Lemole

Acting

Golden Fang Daughter

Madison Leisle

Acting

Golden Fang Son

Liam Van Joosten

Acting

Golden Fang Father

Matt Doyle

Acting

Smedley

Christian Williams

Acting

Dr. Threeply

Jefferson Mays

Acting

Buddhist Monk

David Prak

Acting

Bodhi

Amy Ferguson

Acting

Zinnia

Emma Dumont

Acting

Jesus Guard (uncredited)

Scott Aschenbrenner

Acting

Patient (uncredited)

Christina Bobrowsky

Acting

Police Officer (uncredited)

Peter Bonilla

Acting

Recording Tech (uncredited)

Gregoer Boru

Acting

Beach Girl (uncredited)

Marianne Bourg

Acting

Harmony (uncredited)

Toyia Brown

Acting

Groupie (uncredited)

Stu Brumbaugh

Acting

Detective (uncredited)

Seth Cash

Acting

Groupie (uncredited)

Laura Lyon Rossi

Acting

Patient (uncredited)

Ashleigh Biller

Acting

Patient (uncredited)

Elizabeth Colunga

Acting

Groupie (uncredited)

Emma Cooper

Acting

Patient (uncredited)

Nick de Graffenreid

Acting

Jesus Guard (uncredited)

Adam Dorsey

Acting

Judge (uncredited)

Ken Edling

Acting

Groupie (uncredited)

Jenna Emery

Acting

Biker (uncredited)

Al Function

Acting

Flight Attendant (uncredited)

Brandy Futch

Acting

Dental Assistant (uncredited)

Lauren Goncher

Acting

Chinese Waitress (uncredited)

Ellen Ho

Acting

Speed Freak (uncredited)

Jessica Huss

Acting

Patient (uncredited)

Robert Peoples

Acting

Auto Mechanic (uncredited)

Dallas James

Acting

Mr. Robinson (uncredited)

Christopher Karl Johnson

Acting

Commando (uncredited)

Timothy Lally

Acting

Beach Girl (uncredited)

Adeana Lane

Acting

Groupie (uncredited)

Kira Legg

Acting

District Attorney (uncredited)

Tracy Ann Lisa

Acting

Patient (uncredited)

Blue LoLan

Acting

Mormon FBI Agent (uncredited)

Jacob Lyman

Acting

Flight Attendant (uncredited)

Amanda Maddox

Acting

Groupie (uncredited)

Emilee Madrak

Acting

Dental Assistant (uncredited)

Kirstin Masters

Acting

Police Officer (uncredited)

Zach McMahon

Acting

Patient (uncredited)

Chelsea O'Toole

Acting

Commando (uncredited)

Shaun Parker

Acting

Adrian Prussia's Friend (uncredited)

Rodney J. Richards

Acting

Hippie in Commune (uncredited)

Philip Roosevelt

Acting

Japanese Waiter (uncredited)

Osamu Saito

Acting

Police Officer (uncredited)

Joel Shock

Acting

Detective (uncredited)

Matthew Skomo

Acting

Groupie (uncredited)

Chantal Thuy

Acting

Lourdes (uncredited)

Diana Elizabeth Torres

Acting